JACC Journals Release Series on Age Type Comparison

American College of Cardiology

The JACC family of journals have published an eight-part series on chronological vs. biological aging in relation to heart health. The series of State-of-the-Art Reviews plus introductory commentary are featured across nine journals, including the Journal of the American College of Cardiology (JACC), JACC: Basic to Translation Science, JACC: Heart Failure, JACC: Cardiovascular Imaging, JACC: Clinical Electrophysiology, JACC: Asia, JACC: Advances, JACC: Cardiovascular Interventions and JACC: CardioOncology.

With a focus on cardiovascular disease (CVD), the series underscores the importance of understanding the distinction between chronological and biological aging and how biological factors influence CVD risk, progression and management, even when chronological years may not align. Clinical considerations that can affect the biological aging process and its impact on cardiovascular health are examined, including various biomarkers, genetic factors and lifestyle interventions, emphasizing the need and potential for tailored prevention and treatment strategies.

"There is much for caregivers and cardiovascular researchers to learn about how the linear passing of time from birth to old age, compared with how the accumulation of molecular and cellular changes result in a decline of cognitive and physiological function," said JACC Editor-in-Chief Valentin Fuster, MD, MACC, in his introduction to the series.

The complete list of the JACC Journals Family Series on Chronological vs Biological Aging includes the following articles:

  • JACC

Chronological vs Biological Aging: JACC Journals Family Series (Introduction)

Valentin Fuster

  • JACC: Advances

TAVR in Older Adults: Moving Toward a Comprehensive Geriatric Assessment and Away From Chronological Age

Abdulla A. Damluji, Ashok Krishnaswami, et. al.

  • JACC: Asia

Impact of Aging on Cardiovascular Disease: From Chronological Observation to Biological Insights

Dong Zhao, Jian'an Wang, et. al.

  • JACC: Basic to Translational Science

Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications

Manish Kumar, Ming Xu, et. al.

  • JACC: CardioOncology

Cardiovascular Concerns, Cancer Treatment, and Biological and Chronological Aging in Cancer

Dina Ioffe, Efrat Dotan, et. al.

  • JACC: Cardiovascular Imaging

Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System

Zahra Raisi-Estabragh, Steffen E. Petersen, et. al.

  • JACC: Cardiovascular Interventions

Chronological vs Biological Age in Interventional Cardiology: A Comprehensive Approach to Care for Older Adults

Abdulla A. Damluji, Mohamad Alkhouli, et. al.

  • JACC: Clinical Electrophysiology

Assessing Biological Age: The Potential of ECG Evaluation Using Artificial Intelligence

Francisco Lopez-Jimenez, Zachi I. Attia, et. al.

  • JACC: Heart Failure

Aging in Heart Failure: Embracing Biology Over Chronology

Parag Goyal, Jason Roh, et. al.

View the full list of articles on JACC.org here

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