Police and emergency services are currently at the scene of a fatal crash in Kialla West.
Emergency services were called to the Goulburn Valley Highway following reports a car had left the roadway and struck a tree just after 4pm.
A yet to be formally identified man, who was a passenger in the Holden Commodore, died at the scene.
The female driver has been taken to hospital with non-life threatening injuries.
Police will investigate the cause of the crash and investigators from the Major Collision Investigation unit will attend the scene.
Anyone who witnessed the incident or with dash cam footage is urged to contact Crime Stoppers on 1800 333 000 or visit www.crimestoppersvic.gov.au