Police are investigating a serious two-vehicle crash on Childers Road in the Bundaberg region overnight.
Early information indicates just after 6pm the cars were heading in opposite directions when they collided at Branyan.
The 18-year-old female driver of one vehicle was transported to the Bundaberg Hospital in a critical condition.
The other driver, a 31-year-old man was also taken to the Bundaberg Hospital with non-life threatening injuries.
Anyone with information relating to this incident is urged to contact police.
The Forensic Crash Unit is investigating.