Police are currently on scene after two motorcycles collided in Marysville this morning, Victoria Police say.
It is believed two motorcycles collided head-on, on Marysville-Woods Point Road about 11am.
The two male riders, yet to be formally identified, died at the scene.
The exact circumstances surrounding the collision are being investigated.
Lanes travelling in both directions are closed on Marysville-Woods Point Road between Merchison Street and Cumberland Junction.
Police advise motorists to avoid the area.