Two people have died and a third has been injured following a collision in Mount Eliza late last night.
Investigators believe a vehicle was travelling north on the Nepean Highway when it collided with an oncoming vehicle about 11.15pm.
The driver and passenger of the north bound vehicle died at the scene.
The two are yet to be formally identified.
The male driver of the other vehicle sustained non-life threatening injuries and has been transported to hospital for treatment.
Investigators are appealing for anyone who witnessed the crash or with dash cam footage to contact Crime Stoppers on 1800 333 000 or submit a confidential crime report at www.crimestoppersvic.com.au