Homicide Squad detectives are investigating after a Noble Park woman died in hospital on Friday evening.
The woman, who is aged in her 60s, was initially reported to police as missing by a neighbour on 14 June.
The neighbour had seen the woman with an unknown man outside her property on Marna Court on 7 June and had been unable to contact her since.
The woman was subsequently located in Dandenong Hospital on 16 June with injuries that appeared consistent with being seriously assaulted.
Police spoke with the woman, however she subsequently passed away on Friday, 20 June.
At this time, the exact circumstances surrounding the incident which led to her being injured are still being determined.
However detectives from the Homicide Squad are investigating and her death is being treated as suspicious.
Her next of kin are yet to be notified of her death.
Police have spoken with a 62-year-old Endeavour Hills man in relation to the incident, however he has been released pending further enquiries.
The pair are known to each other.
Detectives are keen to speak to anyone who may have further information about the circumstances leading up to the woman's death.
Anyone with information is urged to contact Crime Stoppers on 1800 333 000 or make a report online at www.crimestoppersvic.com.au