Police are appealing for public assistance to help locate Michael McClatchey.
He was last seen in Hex Street in Footscray about 6.10pm yesterday.
Police and SES are currently conducting a search of the Warrandyte area as investigators believe he may have travelled there.
They also believe he may be using public transport or ride share services to get around.
Police have concerns for Michael's welfare as he has a medical condition and have released an image in the hope someone may recognise him.
He is described as Caucasian in appearance, about 180cm tall, with a thin build, brown hair and a beard.
Anyone who sees Michael or who may have information on his whereabouts is urged to contact Footscray Police Station on 8398 9800.
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