Police are appealing for public assistance to help locate missing woman Xiu.
The 81-year-old was last seen in Vincent Road, Noble Park about 1pm today.
Police and family have concerns for Xiu as she has a medical condition.
She is described as Asian, about 150cm tall with a medium build and short grey hair.
She was last seen wearing a bright purple raincoat and dark grey slacks.
Xiu is known to frequent the Noble Park area.
Police have released an image of Xiu and urge anyone with information on her whereabouts to contact Dandenong Police Station on 9767 7444.