Police are appealing for public assistance to help locate missing Murrumbeena man Guo Quiang Zhu.
The 64-year-old was last seen at Booran Reserve in Glen Huntly Road, Glen Huntly about 3pm on Saturday.
Police and family hold concerns for Guo due to a medical condition.
Investigators have released an image of Guo in the hope someone recognises him and comes forward with information about his whereabouts.
Anyone who sees Guo is urged to contact Caulfield Police Station on 9524 9500