Police are appealing for public assistance to help locate missing woman Gloria.
The 39-year-old Narre Warren woman was last seen about 1pm today on High Street in Berwick, boarding a bus heading towards Westfield Fountain Gate shopping centre.
She is described as 150cm tall with a large build and was wearing a navy-blue hooded jumper, pink tracksuit pants and light grey Nike brand runners.
Gloria is known to frequent the Richmond and Melbourne CBD areas.
There are concerns for Gloria as she has medical conditions.
Police have released an image of Gloria and urge anyone with information on her whereabouts to contact Narre Warren Police Station on 9705 3111.