Police are appealing for witnesses following an alleged road rage incident in Lockwood South on Friday.
It is believed a green Ford Focus hatch and a white Ford panel van were driving erratically on Lockwood Road near the Calder Alternate Highway about 5.30pm.
Investigators have been told the Ford Focus has allegedly driven at the panel van several times at high speed before ramming it off the road in the vicinity of the Lockwood interchange.
It's reported a further altercation then took place before both drivers left the area.
The exact circumstances of the collision are still being investigated.
Police are urging anyone with dash-cam footage or who may have any information relating to this collision to contact Crime Stoppers on 1800 333 000 or visit www.crimestoppersvic.com.au