Police are appealing for public assistance to help locate missing Seymour woman Judith Rapley, Victoria Police say.
The 65-year-old was last leaving her home address on Hanley Crescent about 7am yesterday.
Police and family have concerns for Judith as she has a medical condition which requires medication and this behaviour is out of character.
Judith is described as about 170cm tall with a medium build, dyed blonde hair and brown eyes.
She is known to frequent the Yarraville, Roxburgh Park, Sunbury and Blackburn South areas.
Investigators have released an image of Judith in the hope that someone may recognise her and provide information on her current whereabouts.
Anyone who sees Judith is urged to contact Seymour Police Station on 5735 0200.