The Pacific Highway is closed to southbound traffic 1km south of the Karuah exit after a truck rollover, NSW Police say.
Emergency services called to the scene about 3am (Tuesday 9 October 2018), and found the driver trapped within the cabin.
Rescue teams are working to free the man, who has sustained leg injuries.
Traffic travelling north is urged to slow down due to debris from the crash.
It is now being cleared from the roadway, but motorists are urged to delay travel if at all possible.
Anyone with information about this incident is urged to contact Crime Stoppers.