Police were called to a reception and function centre in Somerton overnight following reports a number of people were involved in a brawl.
Attending police located eight men, with varying injuries, at the Hume Highway convention centre on Saturday 7 December about 1.50am.
The injured were treated by ambulance paramedics on scene with several of the victims transported to hospital.
At this stage police are looking into reports that a number of people were ejected from the organised event before they returned, and a fight broke out.
A crime scene has been established and the investigation into the circumstances surrounding the incident and those involved is ongoing.
Anyone with information is urged to contact Crime Stoppers on 1800 333 000 or log onto www.crimestoppersvic.com.au.