Police are appealing for public assistance to help locate missing woman Melissa Kent.
Melissa, who has Down Syndrome, left her care facility on Corvey Road in Reservoir about 5pm.
The 42-year-old is described as having a short stature and was wearing a blue jumper, leggings and pink slippers.
Investigators have released an image of Melissa in the hope that someone may have information on her current whereabouts.
Anyone who sees Melissa is urged to contact Reservoir Police Station on 9460 6744.