Major Collision Investigation Unit detectives are investigating following a fatal collision at Glen Waverley last night.
Emergency services were called to the intersection of High Street Road and Arianne Road to reports two cars had collided about 8.55pm.
A 68-year-old Glen Waverley woman, who was a passenger in a gold coloured Mitsubishi sedan, sustained life-threatening injuries and was transported to hospital.
Sadly, she later died from her injuries
The driver of the Mitsubishi, a 66-year-old Glen Waverley man, sustained serious injuries and was transported to hospital.
The 19-year-old driver of the other vehicle, a white Ford sedan, sustained minor injuries.
The exact circumstances surrounding the collision are yet to be determined and investigations are ongoing.
Police would like to speak to anyone who may have witnessed the collision or who has dashcam footage, to contact Crime Stoppers on 1800 333 000 or submit a confidential report via www.crimestoppersvic.com.au