Major Collision Investigation Unit detectives are investigating the circumstances following a fatal collision in Hoppers Crossing early this morning.
It is alleged a stolen grey Skoda sedan was pursing another vehicle, in what appears to be an attempted carjacking along Derrimut Road just after 12am.
The Skoda collided with the rear of that vehicle, a Toyota sedan which managed to safely flee the scene.
A short time later the Skoda also collided with a Ford sedan and a Ford Ranger causing the Skoda to roll several times.
One of the occupants inside the Skoda a teenaged boy died at the scene.
A 17-year-old boy and a 16-year-old girl both from the Wyndham area were taken to hospital with non-life-threatening injuries under police guard.
A 16-year-old girl from the Wyndham area was arrested and taken to hospital with minor injuries, she has since been released from hospital and is expected to be interviewed later this morning.
All occupants inside the Toyota, and both Fords suffered minor injuries.
Checks have revealed the Skoda was stolen from an address on Yellow Box Street, Maidstone between 11 and 12 of March.
Any witnesses or anyone with dashcam/CCTV footage is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au