Police and emergency services remain on the scene of a serious crash on Goderich Street in Invermay in Launceston.
Police and emergency services were alerted to the crash at 6.50am this morning.
Initial investigations suggest that a crash occurred between a truck and a car, with the truck veering into a nearby house.
The truck driver and the two occupants of the car have been seriously injured and are receiving medical treatment.
No one else was injured in the incident, including the occupants of the house.
The south bound and north bound lanes of Goderich Street are closed.
Police are working hard to clear the scene but traffic delays are expected.
Motorists are advised to use Vermont Road and Invermay Road instead until further notice.
Media please be advised that Acting Inspector Andrew Hanson will be available for interview on the scene at 10am.