A female has died after being shot by police in South Melbourne this evening.
Officers were called to Cecil Street following reports of a male with a machete around 5pm.
Police located a male and whilst he was being arrested, a vehicle was driven at a police officer, striking them.
The officer shot at the offending vehicle, striking a female driver and her male passenger.
The 34-year-old female has died at the scene, while the 26-year-old male has been taken to hospital with non-life-threatening injuries.
The male Senior Constable has been taken to hospital with serious but non-life-threatening-injuries.
Homicide Squad detectives will now investigate the matter with oversight from Professional Standards Command, as is standard procedure for a fatal police shooting.
Anyone who witnessed the incident or with further information is urged to contact Crime Stoppers on1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au