First-Gen Antihistamines Linked to Seizures in Children

JAMA Network

About The Study: Prescriptions for first-generation antihistamines were associated with a 22.0% higher seizure risk in children, especially in those ages 6 to 24 months in this cohort study. These findings emphasize the need for careful and judicious prescription of first-generation antihistamines in young children and underline the need for further research to elucidate associations between antihistamine prescriptions and seizure risk.

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