JAMA Network
About The Study: Compared with usual care, use of the PETRUSHKA tool increased the number of patients still taking their antidepressant at 8 weeks and improved depressive and anxiety symptoms at 24 weeks. However, lack of a double-blind design and the large amount of missing data limit the validity of these results. The PETRUSHKA tool is a web-based clinical decision-support system combining clinical and demographic predictors with patient preferences to personalize antidepressant treatment.
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