Major Collision Investigation Unit detectives are investigating the circumstances surrounding a fatal collision in Corio this afternoon.
It is believed a truck travelling north on Bacchus Marsh Road collided with a car at the intersection of the Ring Road just after 2pm.
Sadly, the driver of the car, a 64-year-old Bell Park woman, died at the scene.
A 2-year-old Lovely Banks girl was airlifted to hospital with serious injuries.
The truck driver, a 38-year-old Clyde man, was not injured and is assisting police with their enquiries.
The exact cause of the crash is yet to be determined and investigations continue.
Police will prepare a report for Coroner and ask that anyone who witnessed the crash, or who may have dash cam footage, call Crime Stoppers on 1800 333 000 or submit a confidential report at www.crimestoppersvic.com.au.