Specialist teams have been working around the clock carrying out investigations into damage that has been discovered underneath the road.
During planned maintenance works, it was discovered that water damage had corroded some of the steel works underneath the road.
Highways England has closed the eastbound carriageway, which carries traffic out of the city centre, while this damage is thoroughly investigated and these investigations will be continuing across the weekend.
Head of service delivery at Highways England Adrian Oulds said:
Whilst we know that the structure itself remains safe we need to fully assess the extent of the water corrosion before opening this busy road up to traffic. We are striving to get the bridge partially open early next week.
We appreciate road closures are frustrating for people but the safety of the public and road users is always the priority for Highways England.
We are grateful to drivers for their patience and would urge them to allow extra time for journeys and avoid the area if possible.
To alleviate congestion, Highways England has stepped up its traffic officer patrol service in the area to help motorists with the diversion route.
We're also working closely with the emergency services to ensure medical and emergency access can be maintained while the road is closed.
Free recovery is also in place for vehicles travelling in the area while the closure remains in place.
The diversion route is in place from A52 Queens Drive junction to A52 Nottingham Wheatcroft junction, with motorists advised to leave extra time for their journeys throughout the day and the weekend.
