A woman has died following a two car collision in Wyuna, near Kyabram, earlier this afternoon, Victoria Police say.
The crash happened at the intersection of Trevakis Road with the Echuca-Mooroopna Road about 3pm.
It is believed the female driver, a 33-year-old Cobram woman, was travelling south on Trevakis Road, when she collided with a twin-cab utility travelling west on the Echuca-Mooroopna Road.
The woman died at the scene while the driver of the other vehicle, a Kyabram man aged in his 20s, was airlifted to a Melbourne hospital with serious injuries.
Anyone with information or who witnessed the collision is urged to contact Crime Stoppers.