Think big. Despite its research topic, this could well be the motto of the Graphene Flagship, which was launched in 2013: With an overall budget of one billion Euros, it was Europe's largest research initiative to date, alongside the Human Brain Flagship, which was launched at the same time. The same applies to the review article on the effects of graphene and related materials on health and the environment, which Empa researchers Peter Wick and Tina Bürki just published together with 30 international colleagues in the scientific journal ACS Nano; on 57 pages, they summarize the findings on the health and ecological risks of graphene materials, the reference list includes almost 500 original publications.
A wealth of knowledge – which also gives the all-clear. "We have investigated the potential acute effects of various graphene and graphene-like materials on the lungs, in the gastrointestinal tract and in the placenta – and no serious acute cell-damaging effects were observed in any of the studies," says Wick, summarizing the results. Although stress reactions can certainly occur in lung cells, the tissue recovers rather quickly. However, some of the newer 2D materials such as boron nitrides, transition metal dichalcogenides, phosphenes and MXenes (see info box) have not yet been investigated much, Wick points out; further investigations were needed here.
In their analyses, Wick and Co. did not limit themselves to newly produced graphene-like materials, but also looked at the entire life cycle of various applications of graphene-containing materials. In other words, they investigated questions such as: What happens when these materials are abraded or burnt? Are graphene particles released, and can this fine dust harm cells, tissues or the environment?
One example: The addition of a few percent graphene to polymers, such as epoxy resins or polyamides, significantly improves material properties such as mechanical stability or conductivity, but the abrasion particles do not cause any graphene-specific nanotoxic effect on the cells and tissues tested. Wick's team will be able to continue this research even after the flagship project has come to an end, also thanks to funding from the EU as part of so-called Spearhead projects, of which Wick is deputy head.
