Western Road Policing Services intercepted 22 speeding drivers during a targeted operation on the Ridgley Highway yesterday afternoon.
Acting Inspector Martin Parker said three of the drivers were travelling at speeds of more than 30 kilometres above the limit.
"It is incredibly disappointing that these drivers chose to put not only their own life at risk, but the lives of other road users by speeding," he said.
"They were also travelling on wet roads, making the situation even more dangerous.
"We are urging all road users to please make good choices and help us keep everyone safe."
During the five-hour operation, police also issued infringements for two drivers with unregistered vehicles, and issued two defect notices.
Incidents of dangerous driving can be reported to police on 131 444 or Triple Zero (000) in an emergency. Reports can also be made via Crime Stoppers Tasmania on 1800 333 000 or at crimestopperstas.com.au. Information can be provided anonymously.
