Missing woman Priscilla Lucas

Police are appealing for public assistance to help locate missing Corinella woman Priscilla Lucas.

The 43-year-old was last seen at a motel on South Gippsland Highway, Cranbourne on Tuesday 17 March.

Police and family hold concerns for Priscilla's welfare due to a medical condition.

Investigators have released an image of Priscilla in the hope someone recognises her and can provide information on her current whereabouts.

Anyone who sees Priscilla is urged to contact Wonthaggi Police Station on 03 5671 4100.

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