Reston, VA (May 16, 2025)—New research has been published ahead-of-print by The Journal of Nuclear Medicine (JNM). JNM is published by the Society of Nuclear Medicine and Molecular Imaging, an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes.
Summaries of the newly published research articles are provided below.
DARPin Pretargeting Breakthrough Could Boost Cancer Imaging
Scientists have adapted a powerful tumor-targeting protein, DARPin G3, for precision imaging using a novel pretargeting system. By attaching a DNA-like peptide nucleic acid sequence, they achieved specific tumor targeting with dramatically reduced kidney and liver uptake in mice—offering a promising strategy for safer and more effective cancer diagnostics.
GRPR: A Universal Target in Cancer Imaging and Therapy
GRPR, a receptor overexpressed in many cancers, is emerging as a powerful tool for both imaging and treatment. This review explores the development and clinical use of GRPR-targeting compounds, highlighting their potential to advance personalized cancer care across multiple tumor types.
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