A Shepparton woman has died following a single car crash in Tatura about 4.30pm today.
The 49-year-old was driving east on Ferguson Road when her car left the road and hit a tree.
Emergency services attended and freed the woman, however she died on-route to hospital.
The woman was the sole occupant of the vehicle and investigations are ongoing.
Anyone with information or who witnessed the collision is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au