Major Collision Investigation Unit detectives are investigating the circumstances surrounding a fatal crash near Swan Hill this afternoon.
A vehicle containing four occupants was travelling north on Swan Hill-Donald Road at Lalbert when it lost control and rolled several times shortly before 4.30pm.
A female passenger in the vehicle was declared deceased at the scene.
The female driver was taken to hospital where she remains under police guard.
A second female passenger was airlifted to hospital with serious injuries and a male passenger was taken by road to hospital with minor injuries.
The exact circumstances surrounding the crash are yet to be determined and an investigation is ongoing.
Anyone who witnessed the crash, has CCTV or dashcam footage, or anyone with information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au