About 10.55am, a white Honda CR-V station sedan was travelling north on Forrest Highway near Greenlands Road when the vehicle lost control and rolled.
The 45-year-old male driver and two juvenile passengers were conveyed to Peel Health Campus for treatment of minor injuries.
A 42-year-old female passenger was conveyed to Royal Perth Hospital for treatment of serious injuries.
Major Crash investigators are conducting an examination of the scene and are appealing for any witnesses to report information online at www.crimestopperswa.com.au or call Crime Stoppers on 1800 333 000.
Dash-cam or mobile phone vision relating to this crash can uploaded directly to investigators via this link: https://wapf.au.evidence.com/axon/community-request/public/mcis2026-211… ;