Police are appealing for witnesses after a motorbike rider crashed into a Corolla on Citylink last night.
Emergency services were called to the crash which occurred on the inbound lanes near Moreland Road about 11.30pm.
The rider, believed to be a man in his 40s, was taken to hospital with serious injuries.
The driver of the car, a man in his 20s, stopped at the scene and has spoken to police.
Anyone who witnessed the crash or a red and black 2001 Suzuki GSX100 on Citylink or Bell Street prior to the crash is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential crime report at www.crimestoppersvic.com.au