JAMA Network
About The Studies: This issue of JAMA includes three studies on colorectal cancer incidence and screening among younger U.S. adults.
Colorectal Cancer Incidence in US Adults After Recommendations for Earlier Screening
After a stable 15-year trend, local-stage colorectal cancer (CRC) incidence increased steeply in adults ages 45 to 49 during 2019-2022, including a 50% relative increase between 2021 and 2022. This trend contrasts with consistent increases of distant-stage diagnoses in this age group and likely reflects diagnosis of prevalent asymptomatic cancer through first-time screening due to recommendations for adults to begin screening at age 45 instead of age 50.
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