The United States has launched a new ' America First Global Health Strategy ' which sets out a new and tailored focus for PEPFAR, working closely with countries most affected by HIV
GENEVA, 18 September 2025-UNAIDS welcomes reaffirmed leadership from the United States in the AIDS response and its continued commitment to saving lives through the United States President's Emergency Plan For AIDS Relief (PEPFAR). In its new strategy, released today, the US is placing emphasis on global HIV targets, country partnerships and resilient and durable health systems. It stresses that national self-reliance is critical to achieving and sustaining the shared global objective of ending AIDS as a public health threat.
The new strategy highlights several of UNAIDS' global HIV targets as key benchmarks for US foreign health assistance, including:
- Ensuring that 95% of people living with HIV are aware of their HIV status, 95% of those who know their status are receiving lifesaving HIV treatment, and 95% of those on treatment achieve viral suppression
- Achieving a 90% reduction in new HIV infections by 2030 (compared to 2010 levels)
- Achieving a 90% reduction in AIDS-related deaths by 2030 (compared to 2010 levels)
- Eliminating mother-to-child transmission of HIV in high-burden countries
This timely initiative underscores the continued support of the American people and the US Government in the historic effort to end AIDS-one of the greatest public health challenges of our time. By prioritizing results-driven targets like the UNAIDS 95-95-95 and 90% reduction in new infections by 2030, the US Government will help save millions more lives and accelerate progress to end AIDS.
UNAIDS remains firmly committed to advance and strengthen its long-standing, strategic partnership with the US Government and will continue to work hand-in-hand with PEPFAR to support countries to sustain durable, country-led HIV responses. UNAIDS will work closely together with the US Government in this historic effort to end AIDS-one that saves lives, strengthens global partnerships, makes the world safer and stronger, and brings us all closer to a world without AIDS.
UNAIDS
The Joint United Nations Programme on HIV/AIDS (UNAIDS) leads and inspires the world to achieve its shared vision of zero new HIV infections, zero discrimination and zero AIDS-related deaths. UNAIDS unites the efforts of 11 UN organizations-UNHCR, UNICEF, WFP, UNDP, UNFPA, UNODC, UN Women, ILO, UNESCO, WHO and the World Bank-and works closely with global and national partners towards ending the AIDS epidemic by 2030 as part of the Sustainable Development Goals. Learn more at unaids.org
