First volunteers on COVID-19 human challenge study leave quarantine

The UK's COVID-19 human challenge study has reached its first milestone after administering virus to three volunteers in a controlled clinical setting

The first participants recruited to the landmark trial have now completed a period of quarantine at the Royal Free Hospital in London. They will now continue to be monitored by the clinical team.

"This is vital research to understand the course of disease in those with mild infections and to investigate the detailed natural history of SARS-CoV-2 infection." Peter Openshaw Professor of Experimental Medicine

Participants were inoculated with a low dose of SARS-CoV-2, introduced via droplets in the nose, and carefully monitored by clinical staff in a controlled environment over a two-week period.

The team reports no complications, confirming the participants are in good health and have been discharged from the facility after meeting the quarantine discharge criteria.

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