About The Study: This decision analytic model showed that within the context of a high SARS-CoV-2 probability, monoclonal antibodies pre-exposure prophylaxis (mAbs PrEP) provision was cost-saving when provided to individuals at increased risk of severe COVID-19 if drug prices decrease to $275 and effectiveness is 75% or higher. When newer mAbs PrEP combinations become available, guidance on implementation should be formulated ensuring a fast rollout. Nevertheless, advocacy for mAbs PrEP use and critical discussion on drug prices are necessary to ensuring cost-effectiveness for different epidemic settings.
Authors: Stephanie Popping, M.D., Ph.D., of the University of Amsterdam, is the corresponding author.
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(doi:10.1001/jamanetworkopen.2023.21985)
