Police are investigating a three-vehicle crash in Casula last night, NSW Police say.
About 9.15pm today, emergency services were called to the intersection of Holston Street and the Hume Highway following reports of a crash.
Initial investigations suggest a black Lexus IS250, driven by a 51-year-old woman, crashed into a silver Mazda hatch, which in turn crashed into a black Lexus sedan, at the intersection.
The 51-year-old woman was treated at the scene by Ambulance Paramedics before being taken to Liverpool Hospital, where she remains in a critical condition.
The driver of the Mazda, a 35-year-old woman, was treated at the scene by Ambulance Paramedics before being taken to Liverpool Hospital with non-life-threatening injuries.
The driver of the second Lexus, a 22-year-old man, received minor injuries.
A crime scene was established and examined by specialist officers.
Investigations are continuing and police are urging anyone with information to come forward.
Police are urging anyone with information in relation to this incident to call Crime Stopers.