Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening and routine supplementation for iron deficiency and iron deficiency anemia in pregnant persons to prevent adverse maternal and infant health outcomes. Iron deficiency is the leading cause of anemia during pregnancy. According to survey data from 1999 to 2006, overall estimated prevalence of iron deficiency during pregnancy is near 18% and increases across the three trimesters of pregnancy. An estimated 5% of pregnant persons have iron deficiency anemia. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation is consistent with the 2015 recommendation statement on screening and supplementation for iron deficiency anemia during pregnancy.
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(doi:10.1001/jama.2024.15196)