World-first Vaccine Gives New Hope To Koalas

Dept of Climate Change, Energy, Environment & Water

Australia is famous for its inventions and scientific breakthroughs. From Wi-Fi to the cochlear ear, we're always taking on big problems and trying to find a smarter way.

Now, our latest world first is a vaccine that will protect koalas against chlamydia.

Chlamydia is one of the biggest threats to koalas. It is an infection that can cause intense suffering. As well as pain, it can lead to blindness, infertility and even death. In some wild populations, up to 70% of koalas are infected. For a species under pressure, chlamydia is devastating.

Koala laying on towel with paw being held by human hands.
A koala is prepped for the new vaccine. Image credit: UniSc

But now, there's new hope in the fight against this disease. A single-dose vaccine has been approved, thanks to the hard work of researchers at the University of the Sunshine Coast's Centre for Bioinnovation. The team, led by Professor Peter Timms has worked for more than 10 years on the new treatment.

Following a $749,000 grant from the Australian Government's $76 million Saving Koalas Fund, the project has moved from research to reality. Now approved by the Australian Pesticides and Veterinary Medicines Authority, the vaccine can be used by wildlife hospitals and vets in clinics and the field.

Trials included hundreds of koalas, both in care and in the wild. The largest long-term study found the vaccine reduced chlamydia-related deaths in wild populations by at least 65%. It also reduced infection, lowered the chance of symptoms developing, and in some cases, even reversed them.

Until now, antibiotics were the only treatment option. While antibiotics fought the disease, administering them widely in wild colonies is difficult. Antibiotics also disrupt a koala's ability to digest eucalyptus leaves - their only food - and leave them open to reinfection. The new vaccine offers a safer and more effective way to protect koalas.

This milestone is the result of years of persistence and teamwork between researchers, carers and communities. It also reminds us that Australian science is incredible at solving problems that matter to our natural environment, community and future.

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