6 Neuroendocrine Tumour Symptoms Not to Ignore

Cancer Council NSW
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Ahead of Rare Cancer Day on 26 June, it's important to raise awareness of conditions like neuroendocrine tumours (NETs). NETs are uncommon cancers that can develop in different parts of the body, most often in the digestive system, lungs or pancreas.

Because symptoms can be vague or mistaken for other conditions, NETs are often diagnosed at a later stage. Understanding the possible signs can help support earlier diagnosis and better outcomes.

Here are six common symptoms you should be aware of:

1. Abdominal pain and bloating

NETs that develop in the gastrointestinal tract may cause ongoing pain or discomfort in the abdomen. This might include bloating, cramping or a feeling of fullness that doesn't go away.

Some people also experience changes in bowel habits, such as diarrhoea or constipation.

2. Flushing and facial redness

Some NETs produce hormones that affect how the body functions.

One common symptom is sudden episodes of facial flushing or redness, often affecting the cheeks or neck. This can happen with other symptoms such as diarrhoea, wheezing or a racing heartbeat.

3. Unexplained weight loss

Losing weight without trying, especially when combined with fatigue or reduced appetite, may be a sign of an underlying health issue.

NETs can impact how the body digests food and absorbs nutrients, leading to weight loss or nutritional deficiencies.

4. Constant fatigue and weakness

Chronic tiredness, weakness or feeling low in energy may occur with NETs. These symptoms may be caused by hormonal imbalances or metabolic changes.

Some people also report trouble concentrating or muscle cramps.

5. Changes in bowel or urinary habits

Some NETs affect the digestive or urinary system, which can cause symptoms such as diarrhoea, blood in stool, or increased urinary frequency.

6. Respiratory symptoms

When NETs develop in the lungs, they may cause coughing, wheezing, chest pain or shortness of breath.

Lung NETs can affect respiratory function, which can cause symptoms like cough, wheezing, chest discomfort, or recurrent respiratory infections.

While most of these symptoms can be caused by other conditions that are not cancer, if you notice something unusual or persistent, talk to your doctor.

Early detection can improve treatment options and outcomes. Trust your instincts and seek medical advice if you're concerned about your health.


If you want to learn more, please visit our pages about neuroendocrine tumours and rare and less common cancers.

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