Gender Affirming Hormone Therapy has positive impact on well-being

European Society of Endocrinology

New evidence shows that people who have undergone Gender Affirming Hormone Therapy report high

grades of satisfaction with both the physical and psychological effects. A new study on this topic, carried out

by researchers in Portugal, will be presented today (21 May 2022) at the 24th European Congress of

Endocrinology in Milan, Italy.

Gender Affirming Hormone Therapy (GAHT) aims to align the characteristics of an individual with their gender

identity. Typically, this means altering a person’s hormone levels to match their gender identity. Dr. Miguel

Saraiva and team at the Centro Hospitalar Universitário do Porto – Hospital de Santo António wanted to

understand to what degree this type of therapy impacts the lives of those affected. To this end, the team

conducted a cross-sectional study in March 2021, collecting data via an online questionnaire. This

questionnaire was distributed to adults living in Portugal who had undergone GAHT for at least one year. The

questionnaire used an ordinal scale ranging from 0 (worst result) to 6 (best result). With a median age of 25

years, 142 people completed the questionnaire: 101 for masculinising GAHT and 41 for feminising GAHT. The

overall satisfaction with GAHT was rated at 5.0 points on a scale of 6.0.

The high score was consistent across several metrics and shows that GAHT positively influences self-esteem,

well-being, and social/familial relationships in the Portuguese adult transgender population. GAHT similarly

appears to reduce suicidal ideation, having a significant impact on the quality of life of the people who benefit

from it.

“The well-being of transgender patients is very important, and we are happy to document the very positive

result of Gender Affirming Hormone Therapy on the Portuguese transgender population,” concluded Dr.



Society of Endocrinology

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