Genotype-Guided Antidepressant Prescribing Revolution

JAMA Network

About The Study: In this randomized clinical trial, genotype-guided prescribing of selective serotonin reuptake inhibitors (SSRIs) did not improve control of depression symptoms at 3 months compared with usual care but was associated with higher depression remission rates at 6 months. These findings suggest a possible longer-term clinical benefit and indicate that future studies should focus on the durability and long-term impact of genotype-guided prescribing in the management of depressive symptoms.

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