KAIST Unveils Chip for Predicting Drug Side Effects

Korea Advanced Institute of Science and Technology

<(From Left) Dr.Jaesang Kim, Professor Seongyun Jeon>

Rhabdomyolysis is a condition in which muscle damage—often caused by drug intake—can lead to impaired kidney function and acute kidney failure. However, there have been limitations in directly observing how muscle and kidney damage influence each other simultaneously within the human body. KAIST researchers have developed a new device that can precisely reproduce such inter-organ interactions in a laboratory setting.

KAIST announced on the 5th of January that a research team led by Professor Seongyun Jeon of the Department of Mechanical Engineering, in collaboration with Professor Gi-Dong Sim's team from the same department and Professor Sejoong Kim of Seoul National University Hospital, has developed a system that can recreate, in the laboratory, the process by which drug-induced muscle damage leads to kidney injury.

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