The integration of biological organisms into synthetic structures offers a radical new pathway for developing intelligent, self-powered materials. Researchers have pioneered an innovative approach to bio-manufacturing by using light-based 3D printing to engineer living material systems capable of localized environmental processing.

By embedding marine dinoflagellates (Pyrocystis lunula) into biocompatible hydrogels via Digital Light Processing (DLP), the collaborative team from the Complex Materials Group , the Laboratory for Nanometallurgy and the external page Cellulose and Wood Materials Laboratory at Empa successfully fabricated intricate, complex geometries including sponge-like gyroid architectures and porous robotic components that were previously impossible to manufacture. These microalgae utilize an internal biological machinery that translates mechanical stress directly into visible blue light through mechanoluminescence.
A defining characteristic of these 3D-printed living gels is their operation as autonomous material systems. The embedded cells function as a biological "band-pass filter," responding only when specific thresholds of mechanical force or velocity are crossed. This allows the material to process environmental data locally, mimicking the decentralized sensing networks found in soft-bodied marine organisms like the octopus, thereby bypassing the need for traditional central microprocessors or heavy battery packs. Crucially, because these systems communicate using light, information transfer is exceptionally fast and simple to process and eliminates the need for complex internal wiring.
By merging the geometric freedom of advanced additive manufacturing with the metabolic activity of living microorganisms, this research establishes a foundational framework for a new generation of self-sustained, intelligent soft matter.
R. Boons, M. Steinacher, H. Galinski, V. Niggel, T. Zimmermann, G. Nyström, G. Siqueira, A. R. Studart, Light-based 3D printing of mechanoluminescent living gels loaded with dinoflagellates. Science Advances 12, eadz0017 (2026). external page DOI:10.1126/sciadv.adz0017