Cancer Screening Trials: Mortality vs Stage End Points

JAMA Network

About The Study: In this systematic review and meta-analysis that included 41 randomized clinical trials of cancer screening, incidence of late-stage cancer may be a suitable alternative end point to cancer-specific mortality for some cancer types, but is not suitable for others. These results have implications for clinical trials of multicancer screening tests.

Authors: Hilary A. Robbins, Ph.D., M.H.S., M.S.P.H., of the International Agency for Research on Cancer in Lyon, France, is the corresponding author.

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(doi:10.1001/jama.2024.5814)

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