Pregnancy Opioid Exposure Increases Preterm Delivery Risk

JAMA Network

About The Study: In this study of 251,000 pregnant patients with Tennessee Medicaid and without opioid use disorder, a positive association was found between total prescription opioid dose dispensed and the odds of spontaneous preterm birth. These findings support guidance to minimize opioid exposure during pregnancy and prescribe the lowest dose necessary.

Authors: Sarah S. Osmundson, M.D., M.S., of the Vanderbilt University Medical Center in Nashville, is the corresponding author.

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(doi:10.1001/jamanetworkopen.2023.55990)

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