Career Of Unlocking Genetic Drivers Of Addiction

As director of the Center for Studies of Addiction at the University of Pennsylvania, Henry Kranzler, MD has spent decades exploring how genetic risk factors influence vulnerability to alcohol use disorder (AUD), how those insights can inform targeted approaches to care, and preventing the adverse effects of heavy alcohol consumption.

One notable study explored the connection between alcohol consumption and brain volume, providing compelling evidence that long-term alcohol use may contribute to alcohol-related brain shrinkage—a finding with implications for both public health policy and the public conversation around the impact of alcohol.

Kranzler has recently been recognized with major awards in his field for his far-reaching impact. However, it's a career that almost didn't happen.

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