About The Study: In this study of 3,635 female participants in the U.S., premenstrual disorders (PMDs) were associated with increased risks of early menopause and moderate or severe vasomotor symptoms (VMS). PMDs may be indicative of underlying physiology linked to early menopause and VMS, suggesting a phenotype observable during the reproductive years that may allow clinicians to target women at risk of earlier menopause and subsequent health risks later in the life course.
Authors: Yihui Yang, M.P.H., and Donghao Lu, M.D., Ph.D., of the Karolinska Institutet in Stockholm, Sweden are the corresponding authors.
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(doi: 10.1001/jamanetworkopen.2023.34545)