NeurO2ChipH Project Receives NWO Funding

The NeurO2ChipH has been granted funding through the Open Technology Programme from Domain Applied and Engineering Sciences of the Dutch Research Council (NWO). The NeurO2ChipH is a joint initiative of Wageningen University, Radboud UMC and the University of Twente. The Wageningen University contribution will be carried out by chair group Human and Animal Physiology.

To function properly, neuronal brain cells are organized in complex interacting networks. These networks rely on an optimal coupling between electrical activity/connectivity and metabolic/redox state in space and time. A lack of appropriate in vitro experimental tools prevents in-depth understanding of this metabolo-functional coupling. The NeurO2ChipH project aims to develop a novel on-chip technology for integrated analysis of neuronal network metabolofunction in space and time.

Partnership

For this project Wageningen University, Radboud UMC and University of Twente join forces with three corporate partners to develop the novel on-chip technology. The Wageningen University part will be carried out at the chair group Human and Animal Physiology and involves professor Jaap Keijer (co-applicant), Sander Grefte, Vincent de Boer and Werner Koopman (coordinator). According to the HAP team NeurO2ChipH technology will crucially impact on basic science and deliver a novel intervention screening tool with the potential to reduce the number of animal studies.

One of seven

The NeurO2ChipH is one of the seven projects that were granted funding by the Open Technology Programme of the Dutch Research Council (NWO). NWO is contributing over 5.3 million euros to these application-oriented technical-scientific projects. Industry and other organizations add over 700 thousand euros. NWO is one of the most important science funding bodies in the Netherlands.

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