JAMA Network
About The Study: In this randomized clinical trial, early treatment with metformin was not superior to placebo for the composite primary outcome of insulin initiation or a fasting glucose level of 5.1 mmol/L or greater at gestation weeks 32 or 38. Prespecified secondary outcome data support further investigation of metformin in larger clinical trials.
Authors: Fidelma Dunne, Ph.D., of the University of Galway in Galway, Ireland, is the corresponding author.
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(doi:10.1001/jama.2023.19869)
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